Sudo cp ~/build/VTK/bin/libQVTKWidgetPlugin.so /usr/lib/qt4/plugins/designer To use QVTKWidget in the QT4 Designer, you must: You must have configured Qt with -opengl (and maybe -multimedia?) or you will get a 'Qt QTOPENGL library not found.' CMake error when configuring VTK. Instead, set VTK_Group_Qt=OFF, Module_vtkGUISupportQt=ON, and Module_vtkGUISupportQtOpenGL=ON. If your Qt was not built with Webkit, VTK_Group_Qt will complain. You must turn on the following options in the advanced VTK build configuration: